Modeling CaMKII-mediated regulation of L-type Ca(2+) channels and ryanodine receptors in the heart

Excitation-contraction coupling (ECC) in the cardiac myocyte is mediated by a number of highly integrated mechanisms of intracellular Ca(2+) transport. Voltage- and Ca(2+)-dependent L-type Ca(2+) channels (LCCs) allow for Ca(2+) entry into the myocyte, which then binds to nearby ryanodine receptors...

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Detalles Bibliográficos
Autores principales: Greenstein, Joseph L., Foteinou, Panagiota T., Hashambhoy-Ramsay, Yasmin L., Winslow, Raimond L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982069/
https://www.ncbi.nlm.nih.gov/pubmed/24772082
http://dx.doi.org/10.3389/fphar.2014.00060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982069/
https://www.ncbi.nlm.nih.gov/pubmed/24772082
http://dx.doi.org/10.3389/fphar.2014.00060

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