Cargando…

Biophysics, pathophysiology, and pharmacology of ion channel gating pores

Voltage sensor domains (VSDs) are a feature of voltage gated ion channels (VGICs) and voltage sensitive proteins. They are composed of four transmembrane (TM) segments (S1–S4). Currents leaking through VSDs are called omega or gating pore currents. Gating pores are caused by mutations of the highly...

Descripción completa

Detalles Bibliográficos
Autores principales: Moreau, Adrien, Gosselin-Badaroudine, Pascal, Chahine, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982104/
https://www.ncbi.nlm.nih.gov/pubmed/24772081
http://dx.doi.org/10.3389/fphar.2014.00053