Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density

Fragile X syndrome (FXS), the most common heritable form of mental retardation, is characterized by synaptic dysfunction. Synaptic transmission depends critically on presynaptic calcium entry via voltage-gated calcium (Ca(V)) channels. Here we show that the functional expression of neuronal N-type C...

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Detalles Bibliográficos
Autores principales: Ferron, Laurent, Nieto-Rostro, Manuela, Cassidy, John S., Dolphin, Annette C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982139/
https://www.ncbi.nlm.nih.gov/pubmed/24709664
http://dx.doi.org/10.1038/ncomms4628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982139/
https://www.ncbi.nlm.nih.gov/pubmed/24709664
http://dx.doi.org/10.1038/ncomms4628

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