Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous epithelial stem cell proliferation

Kindlin-1 is an integrin tail binding protein that controls integrin activation. Mutations in the FERMT-1 gene lead to Kindler Syndrome in man, which is characterized by skin blistering, premature skin ageing and skin cancer of unknown etiology. Here we show that loss of Kindlin-1 in mouse keratinoc...

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Detalles Bibliográficos
Autores principales: Rognoni, Emanuel, Widmaier, Moritz, Jakobson, Madis, Ruppert, Raphael, Ussar, Siegfried, Katsougkri, Despoina, Böttcher, Ralph T., Lai-Cheong, Joey E., Rifkin, Daniel B., McGrath, John A., Fässler, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982140/
https://www.ncbi.nlm.nih.gov/pubmed/24681597
http://dx.doi.org/10.1038/nm.3490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982140/
https://www.ncbi.nlm.nih.gov/pubmed/24681597
http://dx.doi.org/10.1038/nm.3490

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