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Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous epithelial stem cell proliferation
Kindlin-1 is an integrin tail binding protein that controls integrin activation. Mutations in the FERMT-1 gene lead to Kindler Syndrome in man, which is characterized by skin blistering, premature skin ageing and skin cancer of unknown etiology. Here we show that loss of Kindlin-1 in mouse keratinoc...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982140/ https://www.ncbi.nlm.nih.gov/pubmed/24681597 http://dx.doi.org/10.1038/nm.3490 |