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Optimization strategies for fast detection of positive selection on phylogenetic trees

Motivation: The detection of positive selection is widely used to study gene and genome evolution, but its application remains limited by the high computational cost of existing implementations. We present a series of computational optimizations for more efficient estimation of the likelihood functi...

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Detalles Bibliográficos
Autores principales: Valle, Mario, Schabauer, Hannes, Pacher, Christoph, Stockinger, Heinz, Stamatakis, Alexandros, Robinson-Rechavi, Marc, Salamin, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982156/
https://www.ncbi.nlm.nih.gov/pubmed/24389654
http://dx.doi.org/10.1093/bioinformatics/btt760