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Optimization strategies for fast detection of positive selection on phylogenetic trees
Motivation: The detection of positive selection is widely used to study gene and genome evolution, but its application remains limited by the high computational cost of existing implementations. We present a series of computational optimizations for more efficient estimation of the likelihood functi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982156/ https://www.ncbi.nlm.nih.gov/pubmed/24389654 http://dx.doi.org/10.1093/bioinformatics/btt760 |