HOXA1 drives melanoma tumor growth and metastasis and elicits an invasion gene expression signature that prognosticates clinical outcome

Metastatic melanoma is a highly lethal disease notorious for its aggressive clinical course and eventual resistance to existing therapies. Currently we possess a limited understanding of the genetic events driving melanoma progression, and much effort is focused on identifying pro-metastatic aberrat...

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Detalles Bibliográficos
Autores principales: Wardwell-Ozgo, Joanna, Dogruluk, Turgut, Gifford, Armel, Zhang, Yiqun, Heffernan, Timothy P., van Doorn, Remco, Creighton, Chad J., Chin, Lynda, Scott, Kenneth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982326/
https://www.ncbi.nlm.nih.gov/pubmed/23435427
http://dx.doi.org/10.1038/onc.2013.30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982326/
https://www.ncbi.nlm.nih.gov/pubmed/23435427
http://dx.doi.org/10.1038/onc.2013.30

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