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Identification of Novel Serotonin Transporter Compounds by Virtual Screening

[Image: see text] The serotonin (5-hydroxytryptamine, 5-HT) transporter (SERT) plays an essential role in the termination of serotonergic neurotransmission by removing 5-HT from the synaptic cleft into the presynaptic neuron. It is also of pharmacological importance being targeted by antidepressants...

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Detalles Bibliográficos
Autores principales: Gabrielsen, Mari, Kurczab, Rafał, Siwek, Agata, Wolak, Małgorzata, Ravna, Aina W., Kristiansen, Kurt, Kufareva, Irina, Abagyan, Ruben, Nowak, Gabriel, Chilmonczyk, Zdzisław, Sylte, Ingebrigt, Bojarski, Andrzej J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982395/
https://www.ncbi.nlm.nih.gov/pubmed/24521202
http://dx.doi.org/10.1021/ci400742s