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Unnatural amino acid incorporation in E. coli: current and future applications in the design of therapeutic proteins

Unnatural amino acid (UAA) incorporation by amber codon suppression offers scientists a powerful tool to modify the properties of proteins at will. UAA incorporation has been used for a plethora of fundamental research applications and, more recently, also for the selective modification of therapeut...

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Detalles Bibliográficos
Autores principales: Wals, Kim, Ovaa, Huib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982533/
https://www.ncbi.nlm.nih.gov/pubmed/24790983
http://dx.doi.org/10.3389/fchem.2014.00015