Template Switching During Break-Induced Replication Is Promoted by the Mph1 Helicase in Saccharomyces cerevisiae

Chromosomal double-strand breaks (DSBs) that have only one end with homology to a donor duplex undergo repair by strand invasion followed by replication to the chromosome terminus (break-induced replication, BIR). Using a transformation-based assay system, it was previously shown that BIR could occu...

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Detalles Bibliográficos
Autores principales: Štafa, Anamarija, Donnianni, Roberto A., Timashev, Leonid A., Lam, Alicia F., Symington, Lorraine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982708/
https://www.ncbi.nlm.nih.gov/pubmed/24496010
http://dx.doi.org/10.1534/genetics.114.162297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982708/
https://www.ncbi.nlm.nih.gov/pubmed/24496010
http://dx.doi.org/10.1534/genetics.114.162297

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