Loss of post-transcriptional regulation of DNMT3b by microRNAs: A possible molecular mechanism for the hypermethylation defect observed in a subset of breast cancer cell lines

A hypermethylation defect associated with DNMT hyperactivity and DNMT3b overexpression characterizes a subset of breast cancers and breast cancer cell lines. We analyzed breast cancer cell lines for differential expression of regulatory miRs to determine if loss of miR-mediated post-transcriptional...

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Detalles Bibliográficos
Autores principales: SANDHU, RUPNINDER, RIVENBARK, ASHLEY G., COLEMAN, WILLIAM B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982716/
https://www.ncbi.nlm.nih.gov/pubmed/22664488
http://dx.doi.org/10.3892/ijo.2012.1505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982716/
https://www.ncbi.nlm.nih.gov/pubmed/22664488
http://dx.doi.org/10.3892/ijo.2012.1505

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