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The Regulation of the Expression of ABCG2 Gene through Mitogen-Activated Protein Kinase Pathways in Canine Lymphoid Tumor Cell Lines

Treatments for canine lymphoma often fail, because tumor cells acquire multidrug resistance (MDR). MDR can develop through several mechanisms, among which the overexpression of drug transporters in tumor cells is a well-studied mechanism. ATP-binding cassette sub-family G member 2 (ABCG2) belongs to...

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Detalles Bibliográficos
Autores principales: TOMIYASU, Hirotaka, GOTO-KOSHINO, Yuko, FUJINO, Yasuhito, OHNO, Koichi, TSUJIMOTO, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982807/
https://www.ncbi.nlm.nih.gov/pubmed/24161965
http://dx.doi.org/10.1292/jvms.13-0337