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A Novel Cytomegalovirus-Induced Regulatory-Type T-Cell Subset Increases in Size During Older Life and Links Virus-Specific Immunity to Vascular Pathology

Background. Cytomegalovirus (CMV) infection directly targets vascular endothelium and smooth muscle and at older ages is associated with accelerated vascular pathology and mortality. CMV-specific cellular immunity might directly contribute to this process. Methods. Conventional ex vivo activation–in...

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Detalles Bibliográficos
Autores principales: Terrazzini, Nadia, Bajwa, Martha, Vita, Serena, Cheek, Elizabeth, Thomas, David, Seddiki, Nabila, Smith, Helen, Kern, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982844/
https://www.ncbi.nlm.nih.gov/pubmed/24203779
http://dx.doi.org/10.1093/infdis/jit576