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The Free Energy Landscape of Pseudorotation in 3′–5′ and 2′–5′ Linked Nucleic Acids

[Image: see text] The five-membered furanose ring is a central component of the chemical structure of biological nucleic acids. The conformations of the furanose ring can be analytically described using the concept of pseudorotation, and for RNA and DNA they are dominated by the C(2′)-endo and C(3′)...

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Detalles Bibliográficos
Autores principales: Li, Li, Szostak, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982932/
https://www.ncbi.nlm.nih.gov/pubmed/24499340
http://dx.doi.org/10.1021/ja412079b