Cargando…

Direct Electrochemical Analyses of a Thermophilic Thioredoxin Reductase: Interplay between Conformational Change and Redox Chemistry

[Image: see text] Thioredoxin reductases (TrxRs) are flavin-containing dithioloxidoreductases that couple reduction equivalents from the soluble NAD(P)H pool to the soluble protein thioredoxin (Trx). Previous crystallographic studies of the Escherichia coli enzyme (ecTrxR) have shown that low molecu...

Descripción completa

Detalles Bibliográficos
Autores principales: Hamill, Michael J., Chobot, Sarah E., Hernandez, Hector H., Drennan, Catherine L., Elliott, Sean J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982938/
https://www.ncbi.nlm.nih.gov/pubmed/18717594
http://dx.doi.org/10.1021/bi800676g