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Cobblestone-Area Forming Cells Derived from Patients with Mantle Cell Lymphoma Are Enriched for CD133(+) Tumor-Initiating Cells

Mantle cell lymphoma (MCL) is associated with a significant risk of therapeutic failure and disease relapse, but the biological origin of relapse is poorly understood. Here, we prospectively identify subpopulations of primary MCL cells with different biologic and immunophenotypic features. Using a s...

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Detalles Bibliográficos
Autores principales: Medina, Daniel J., Abass-Shereef, Jeneba, Walton, Kelly, Goodell, Lauri, Aviv, Hana, Strair, Roger K., Budak-Alpdogan, Tulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982953/
https://www.ncbi.nlm.nih.gov/pubmed/24722054
http://dx.doi.org/10.1371/journal.pone.0091042