Efficient Separations of Intact Proteins Using Slip-Flow with Nano-Liquid Chromatography–Mass Spectrometry

[Image: see text] A capillary with a pulled tip, densely packed with silica particles of 0.47 μm in diameter, is shown to provide higher peak capacity and sensitivity in the separation of intact proteins by reversed-phase liquid chromatography–mass spectrometry (LC–MS). For a C18 bonded phase, slip...

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Detalles Bibliográficos
Autores principales: Wu, Zhen, Wei, Bingchuan, Zhang, Ximo, Wirth, Mary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982985/
https://www.ncbi.nlm.nih.gov/pubmed/24383398
http://dx.doi.org/10.1021/ac403233d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982985/
https://www.ncbi.nlm.nih.gov/pubmed/24383398
http://dx.doi.org/10.1021/ac403233d

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