Inhibition of Smurf2 translation by miR-322/503 modulates TGF-β/Smad2 signaling and intestinal epithelial homeostasis

Smad ubiquitin regulatory factor 2 (Smurf2) is an E3 ubiquitin ligase that regulates transforming growth factor β (TGF-β)/Smad signaling and is implicated in a wide variety of cellular responses, but the exact mechanisms that control Smurf2 abundance are largely unknown. Here we identify microRNA-32...

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Detalles Bibliográficos
Autores principales: Cao, Shan, Xiao, Lan, Rao, Jaladanki N., Zou, Tongtong, Liu, Lan, Zhang, Dee, Turner, Douglas J., Gorospe, Myriam, Wang, Jian-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982989/
https://www.ncbi.nlm.nih.gov/pubmed/24554769
http://dx.doi.org/10.1091/mbc.E13-09-0560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982989/
https://www.ncbi.nlm.nih.gov/pubmed/24554769
http://dx.doi.org/10.1091/mbc.E13-09-0560

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