The signaling lipid PI(3,5)P(2) stabilizes V(1)–V(o) sector interactions and activates the V-ATPase

Vacuolar proton-translocating ATPases (V-ATPases) are highly conserved, ATP-driven proton pumps regulated by reversible dissociation of its cytosolic, peripheral V(1) domain from the integral membrane V(o) domain. Multiple stresses induce changes in V(1)-V(o) assembly, but the signaling mechanisms b...

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Detalles Bibliográficos
Autores principales: Li, Sheena Claire, Diakov, Theodore T., Xu, Tao, Tarsio, Maureen, Zhu, Wandi, Couoh-Cardel, Sergio, Weisman, Lois S., Kane, Patricia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982991/
https://www.ncbi.nlm.nih.gov/pubmed/24523285
http://dx.doi.org/10.1091/mbc.E13-10-0563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982991/
https://www.ncbi.nlm.nih.gov/pubmed/24523285
http://dx.doi.org/10.1091/mbc.E13-10-0563

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