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Concentration-dependent lamin assembly and its roles in the localization of other nuclear proteins

The nuclear lamina (NL) consists of lamin polymers and proteins that bind to the polymers. Disruption of NL proteins such as lamin and emerin leads to developmental defects and human diseases. However, the expression of multiple lamins, including lamin-A/C, lamin-B1, and lamin-B2, in mammals has mad...

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Detalles Bibliográficos
Autores principales: Guo, Yuxuan, Kim, Youngjo, Shimi, Takeshi, Goldman, Robert D., Zheng, Yixian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982994/
https://www.ncbi.nlm.nih.gov/pubmed/24523288
http://dx.doi.org/10.1091/mbc.E13-11-0644