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Widespread Use of Non-productive Alternative Splice Sites in Saccharomyces cerevisiae

Saccharomyces cerevisiae has been used as a model system to investigate the mechanisms of pre-mRNA splicing but only a few examples of alternative splice site usage have been described in this organism. Using RNA-Seq analysis of nonsense-mediated mRNA decay (NMD) mutant strains, we show that many S....

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Detalles Bibliográficos
Autores principales: Kawashima, Tadashi, Douglass, Stephen, Gabunilas, Jason, Pellegrini, Matteo, Chanfreau, Guillaume F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983031/
https://www.ncbi.nlm.nih.gov/pubmed/24722551
http://dx.doi.org/10.1371/journal.pgen.1004249