Statistical Power to Detect Genetic (Co)Variance of Complex Traits Using SNP Data in Unrelated Samples

We have recently developed analysis methods (GREML) to estimate the genetic variance of a complex trait/disease and the genetic correlation between two complex traits/diseases using genome-wide single nucleotide polymorphism (SNP) data in unrelated individuals. Here we use analytical derivations and...

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Detalles Bibliográficos
Autores principales: Visscher, Peter M., Hemani, Gibran, Vinkhuyzen, Anna A. E., Chen, Guo-Bo, Lee, Sang Hong, Wray, Naomi R., Goddard, Michael E., Yang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983037/
https://www.ncbi.nlm.nih.gov/pubmed/24721987
http://dx.doi.org/10.1371/journal.pgen.1004269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983037/
https://www.ncbi.nlm.nih.gov/pubmed/24721987
http://dx.doi.org/10.1371/journal.pgen.1004269

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