Cytosolic Peroxidases Protect the Lysosome of Bloodstream African Trypanosomes from Iron-Mediated Membrane Damage

African trypanosomes express three virtually identical non-selenium glutathione peroxidase (Px)-type enzymes which preferably detoxify lipid-derived hydroperoxides. As shown previously, bloodstream Trypanosoma brucei lacking the mitochondrial Px III display only a weak and transient proliferation de...

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Detalles Bibliográficos
Autores principales: Hiller, Corinna, Nissen, Amrei, Benítez, Diego, Comini, Marcelo A., Krauth-Siegel, R. Luise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983053/
https://www.ncbi.nlm.nih.gov/pubmed/24722489
http://dx.doi.org/10.1371/journal.ppat.1004075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983053/
https://www.ncbi.nlm.nih.gov/pubmed/24722489
http://dx.doi.org/10.1371/journal.ppat.1004075

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