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Coxsackievirus-Induced miR-21 Disrupts Cardiomyocyte Interactions via the Downregulation of Intercalated Disk Components

Intercalated disks (ICDs) are substantial connections maintaining cardiac structures and mediating signal communications among cardiomyocytes. Deficiency in ICD components such as desmosomes, fascia adherens and gap junctions leads to heart dysfunction. Coxsackievirus B3 (CVB3) infection induces car...

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Detalles Bibliográficos
Autores principales: Ye, Xin, Zhang, Huifang Mary, Qiu, Ye, Hanson, Paul J., Hemida, Maged Gomaa, Wei, Wei, Hoodless, Pamela A., Chu, Fanny, Yang, Decheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983067/
https://www.ncbi.nlm.nih.gov/pubmed/24722419
http://dx.doi.org/10.1371/journal.ppat.1004070