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A Neutralizing Anti-gH/gL Monoclonal Antibody Is Protective in the Guinea Pig Model of Congenital CMV Infection

Human cytomegalovirus (HCMV) is the most common cause of congenital virus infection. Congenital HCMV infection occurs in 0.2–1% of all births, and causes birth defects and developmental abnormalities, including sensorineural hearing loss and developmental delay. Several key studies have established...

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Detalles Bibliográficos
Autores principales: Auerbach, Marcy R., Yan, Donghong, Vij, Rajesh, Hongo, Jo-Anne, Nakamura, Gerald, Vernes, Jean-Michel, Meng, Y. Gloria, Lein, Samantha, Chan, Pamela, Ross, Jed, Carano, Richard, Deng, Rong, Lewin-Koh, Nicholas, Xu, Min, Feierbach, Becket
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983071/
https://www.ncbi.nlm.nih.gov/pubmed/24722349
http://dx.doi.org/10.1371/journal.ppat.1004060