Antinociceptive Effect of Tetrandrine on LPS-Induced Hyperalgesia via the Inhibition of IKKβ Phosphorylation and the COX-2/PGE(2) Pathway in Mice

Tetrandrine (TET) is a bisbenzylisoquinoline alkaloid that is isolated from the Stephania Tetrandra. It is known to possess anti-inflammatory and immunomodulatory effects. We have shown that TET can effectively suppress the production of bacterial lipopolysaccharide (LPS)-induced inflammatory mediat...

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Detalles Bibliográficos
Autores principales: Zhao, Hengguang, Luo, Fuling, Li, Hongzhong, Zhang, Li, Yi, Yongfen, Wan, Jingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983227/
https://www.ncbi.nlm.nih.gov/pubmed/24722146
http://dx.doi.org/10.1371/journal.pone.0094586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983227/
https://www.ncbi.nlm.nih.gov/pubmed/24722146
http://dx.doi.org/10.1371/journal.pone.0094586

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