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Antinociceptive Effect of Tetrandrine on LPS-Induced Hyperalgesia via the Inhibition of IKKβ Phosphorylation and the COX-2/PGE(2) Pathway in Mice
Tetrandrine (TET) is a bisbenzylisoquinoline alkaloid that is isolated from the Stephania Tetrandra. It is known to possess anti-inflammatory and immunomodulatory effects. We have shown that TET can effectively suppress the production of bacterial lipopolysaccharide (LPS)-induced inflammatory mediat...
Autores principales: | Zhao, Hengguang, Luo, Fuling, Li, Hongzhong, Zhang, Li, Yi, Yongfen, Wan, Jingyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983227/ https://www.ncbi.nlm.nih.gov/pubmed/24722146 http://dx.doi.org/10.1371/journal.pone.0094586 |
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