p150(glued)-Associated Disorders Are Caused by Activation of Intrinsic Apoptotic Pathway

Mutations in p150(glued) cause hereditary motor neuropathy with vocal cord paralysis (HMN7B) and Perry syndrome (PS). Here we show that both overexpression of p150(glued) mutants and knockdown of endogenous p150(glued) induce apoptosis. Overexpression of a p150(glued) plasmid containing either a HMN...

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Detalles Bibliográficos
Autores principales: Ishikawa, Kei-Ichi, Saiki, Shinji, Furuya, Norihiko, Yamada, Daisuke, Imamichi, Yoko, Li, Yuanzhe, Kawajiri, Sumihiro, Sasaki, Hironori, Koike, Masato, Tsuboi, Yoshio, Hattori, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983229/
https://www.ncbi.nlm.nih.gov/pubmed/24722468
http://dx.doi.org/10.1371/journal.pone.0094645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983229/
https://www.ncbi.nlm.nih.gov/pubmed/24722468
http://dx.doi.org/10.1371/journal.pone.0094645

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