HSV-2 Increases TLR4-Dependent Phosphorylated IRFs and IFN-β Induction in Cervical Epithelial Cells

Our previous studies demonstrated that HSV-2 infection up-regulates TLR4 expression and induces NF-kB activity, thereby facilitating innate immune response in human cervical epithelial cells. This process requires involvement of TLR4 adaptors, Mal and MyD88. In the current study, we found that HSV-2...

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Detalles Bibliográficos
Autores principales: Liu, Hongya, Chen, Kai, Feng, Wenqiang, Guo, Juanjuan, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983257/
https://www.ncbi.nlm.nih.gov/pubmed/24722640
http://dx.doi.org/10.1371/journal.pone.0094806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983257/
https://www.ncbi.nlm.nih.gov/pubmed/24722640
http://dx.doi.org/10.1371/journal.pone.0094806

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