Autophagy Inhibitor LRPPRC Suppresses Mitophagy through Interaction with Mitophagy Initiator Parkin

Autophagy plays an important role in tumorigenesis. Mitochondrion-associated protein LRPPRC interacts with MAP1S that interacts with LC3 and bridges autophagy components with microtubules and mitochondria to affect autophagy flux. Dysfunction of LRPPRC and MAP1S is associated with poor survival of o...

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Detalles Bibliográficos
Autores principales: Zou, Jing, Yue, Fei, Li, Wenjiao, Song, Kun, Jiang, Xianhan, Yi, Jinglin, Liu, Leyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983268/
https://www.ncbi.nlm.nih.gov/pubmed/24722279
http://dx.doi.org/10.1371/journal.pone.0094903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983268/
https://www.ncbi.nlm.nih.gov/pubmed/24722279
http://dx.doi.org/10.1371/journal.pone.0094903

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