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Synthesis of Heterocyclic Triads by Pd-Catalyzed Cross-Couplings and Evaluation of Their Cell-Specific Toxicity Profile

[Image: see text] Two complementary approaches for the preparation of linked 5-membered heterocycles were developed. The Pd-catalyzed Suzuki–Miyaura cross-coupling with halogenated furan, thiophene, and selenophene led to higher overall yields, but C,H-bond activation was a more efficient strategy f...

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Detalles Bibliográficos
Autores principales: Salamoun, Joseph, Anderson, Shelby, Burnett, James C., Gussio, Rick, Wipf, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983320/
https://www.ncbi.nlm.nih.gov/pubmed/24641272
http://dx.doi.org/10.1021/ol500620m