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Synthesis of Heterocyclic Triads by Pd-Catalyzed Cross-Couplings and Evaluation of Their Cell-Specific Toxicity Profile
[Image: see text] Two complementary approaches for the preparation of linked 5-membered heterocycles were developed. The Pd-catalyzed Suzuki–Miyaura cross-coupling with halogenated furan, thiophene, and selenophene led to higher overall yields, but C,H-bond activation was a more efficient strategy f...
Autores principales: | Salamoun, Joseph, Anderson, Shelby, Burnett, James C., Gussio, Rick, Wipf, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983320/ https://www.ncbi.nlm.nih.gov/pubmed/24641272 http://dx.doi.org/10.1021/ol500620m |
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