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Diamidine Compounds for Selective Inhibition of Protein Arginine Methyltransferase 1

[Image: see text] Protein arginine methylation is a posttranslational modification critical for a variety of biological processes. Misregulation of protein arginine methyltransferases (PRMTs) has been linked to many pathological conditions. Most current PRMT inhibitors display limited specificity an...

תיאור מלא

מידע ביבליוגרפי
Autores principales: Yan, Leilei, Yan, Chunli, Qian, Kun, Su, Hairui, Kofsky-Wofford, Stephanie A., Lee, Wei-Chao, Zhao, Xinyang, Ho, Meng-Chiao, Ivanov, Ivaylo, Zheng, Yujun George
פורמט: Online Artículo Texto
שפה:English
יצא לאור: American Chemical Society 2014
גישה מקוונת:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983339/
https://www.ncbi.nlm.nih.gov/pubmed/24564570
http://dx.doi.org/10.1021/jm401884z