Diamidine Compounds for Selective Inhibition of Protein Arginine Methyltransferase 1

[Image: see text] Protein arginine methylation is a posttranslational modification critical for a variety of biological processes. Misregulation of protein arginine methyltransferases (PRMTs) has been linked to many pathological conditions. Most current PRMT inhibitors display limited specificity an...

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Detalles Bibliográficos
Autores principales: Yan, Leilei, Yan, Chunli, Qian, Kun, Su, Hairui, Kofsky-Wofford, Stephanie A., Lee, Wei-Chao, Zhao, Xinyang, Ho, Meng-Chiao, Ivanov, Ivaylo, Zheng, Yujun George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983339/
https://www.ncbi.nlm.nih.gov/pubmed/24564570
http://dx.doi.org/10.1021/jm401884z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983339/
https://www.ncbi.nlm.nih.gov/pubmed/24564570
http://dx.doi.org/10.1021/jm401884z

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