Capping Amyloid β-Sheets of the Tau-Amyloid Structure VQIVYK with Hexapeptides Designed To Arrest Growth. An ONIOM and Density Functional Theory Study

[Image: see text] We present ONIOM calculations using density functional theory (DFT) as the high and AM1 as the medium level that explore the abilities of different hexapeptide sequences to terminate the growth of a model for the tau-amyloid implicated in Alzheimer’s disease. We delineate and explo...

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Detalles Bibliográficos
Autores principales: Plumley, Joshua A., Ali-Torres, Jorge, Pohl, Gabor, Dannenberg, J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983367/
https://www.ncbi.nlm.nih.gov/pubmed/24601594
http://dx.doi.org/10.1021/jp501890p

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983367/
https://www.ncbi.nlm.nih.gov/pubmed/24601594
http://dx.doi.org/10.1021/jp501890p

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