Design, Synthesis, and Structure–Activity Relationship of a Novel Series of GluN2C-Selective Potentiators

[Image: see text] NMDA receptors are tetrameric complexes composed of GluN1 and GluN2A–D subunits that mediate a slow Ca(2+)-permeable component of excitatory synaptic transmission. NMDA receptors have been implicated in a wide range of neurological diseases and thus represent an important therapeut...

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Detalles Bibliográficos
Autores principales: Zimmerman, Sommer S., Khatri, Alpa, Garnier-Amblard, Ethel C., Mullasseril, Praseeda, Kurtkaya, Natalie L., Gyoneva, Stefka, Hansen, Kasper B., Traynelis, Stephen F., Liotta, Dennis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983368/
https://www.ncbi.nlm.nih.gov/pubmed/24512267
http://dx.doi.org/10.1021/jm401695d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983368/
https://www.ncbi.nlm.nih.gov/pubmed/24512267
http://dx.doi.org/10.1021/jm401695d

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