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Identification of Clinically Viable Quinolinol Inhibitors of Botulinum Neurotoxin A Light Chain
[Image: see text] Botulinum neurotoxins (BoNT) are the most potent toxins known and a significant bioterrorist threat. Few small molecule compounds have been identified that are active in cell-based or animal models, potentially due to toxin enzyme plasticity. Here we screened commercially available...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983388/ https://www.ncbi.nlm.nih.gov/pubmed/24387280 http://dx.doi.org/10.1021/jm4012164 |