Regulation of soluble guanylate cyclase by matricellular thrombospondins: implications for blood flow

Nitric oxide (NO) maintains cardiovascular health by activating soluble guanylate cyclase (sGC) to increase cellular cGMP levels. Cardiovascular disease is characterized by decreased NO-sGC-cGMP signaling. Pharmacological activators and stimulators of sGC are being actively pursued as therapies for...

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Detalles Bibliográficos
Autores principales: Rogers, Natasha M., Seeger, Franziska, Garcin, Elsa D., Roberts, David D., Isenberg, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983488/
https://www.ncbi.nlm.nih.gov/pubmed/24772092
http://dx.doi.org/10.3389/fphys.2014.00134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983488/
https://www.ncbi.nlm.nih.gov/pubmed/24772092
http://dx.doi.org/10.3389/fphys.2014.00134

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