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Regulation of soluble guanylate cyclase by matricellular thrombospondins: implications for blood flow

Nitric oxide (NO) maintains cardiovascular health by activating soluble guanylate cyclase (sGC) to increase cellular cGMP levels. Cardiovascular disease is characterized by decreased NO-sGC-cGMP signaling. Pharmacological activators and stimulators of sGC are being actively pursued as therapies for...

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Detalles Bibliográficos
Autores principales:	Rogers, Natasha M., Seeger, Franziska, Garcin, Elsa D., Roberts, David D., Isenberg, Jeffrey S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983488/ https://www.ncbi.nlm.nih.gov/pubmed/24772092 http://dx.doi.org/10.3389/fphys.2014.00134

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