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Assessing uncertainty in model parameters based on sparse and noisy experimental data

To perform parametric identification of mathematical models of biological events, experimental data are rare to be sufficient to estimate target behaviors produced by complex non-linear systems. We performed parameter fitting to a cell cycle model with experimental data as an in silico experiment. W...

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Detalles Bibliográficos
Autores principales: Hiroi, Noriko, Swat, Maciej, Funahashi, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983526/
https://www.ncbi.nlm.nih.gov/pubmed/24772089
http://dx.doi.org/10.3389/fphys.2014.00128