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Ultra Q-bodies: quench-based antibody probes that utilize dye-dye interactions with enhanced antigen-dependent fluorescence

Recently, we described a novel reagentless fluorescent biosensor strategy named Quenchbody, which functions via the antigen-dependent removal of the quenching effect on a fluorophore that is attached to a single-chain antibody variable region. To explore the practical utility of Quenchbodies, we pre...

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Detalles Bibliográficos
Autores principales: Abe, Ryoji, Jeong, Hee-Jin, Arakawa, Dai, Dong, Jinhua, Ohashi, Hiroyuki, Kaigome, Rena, Saiki, Fujio, Yamane, Kyosuke, Takagi, Hiroaki, Ueda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983608/
https://www.ncbi.nlm.nih.gov/pubmed/24721819
http://dx.doi.org/10.1038/srep04640