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Enzyme-triggered PEGylated siRNA-nanoparticles for controlled release of siRNA

A key goal of our recent research efforts has been to develop novel ‘triggerable nanoparticle’ systems with real potential utility in vivo. These are designed to be stable from the point of administration until a target site of interest is reached, then triggered for the controlled release of therap...

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Detalles Bibliográficos
Autores principales: Yingyuad, Peerada, Mével, Mathieu, Prata, Carla, Kontogiorgis, Christos, Thanou, Maya, Miller, Andrew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of RNAi and Gene Silencing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983657/
https://www.ncbi.nlm.nih.gov/pubmed/24741375