Cargando…

Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants

Parkinson's disease (PD)-associated Pink1 and Parkin proteins are believed to function in a common pathway controlling mitochondrial clearance and trafficking. Glial cell line-derived neurotrophic factor (GDNF) and its signaling receptor Ret are neuroprotective in toxin-based animal models of P...

Descripción completa

Detalles Bibliográficos
Autores principales: Klein, Pontus, Müller-Rischart, Anne Kathrin, Motori, Elisa, Schönbauer, Cornelia, Schnorrer, Frank, Winklhofer, Konstanze F, Klein, Rüdiger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983680/
https://www.ncbi.nlm.nih.gov/pubmed/24473149
http://dx.doi.org/10.1002/embj.201284290