Cargando…
Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants
Parkinson's disease (PD)-associated Pink1 and Parkin proteins are believed to function in a common pathway controlling mitochondrial clearance and trafficking. Glial cell line-derived neurotrophic factor (GDNF) and its signaling receptor Ret are neuroprotective in toxin-based animal models of P...
Autores principales: | Klein, Pontus, Müller-Rischart, Anne Kathrin, Motori, Elisa, Schönbauer, Cornelia, Schnorrer, Frank, Winklhofer, Konstanze F, Klein, Rüdiger |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983680/ https://www.ncbi.nlm.nih.gov/pubmed/24473149 http://dx.doi.org/10.1002/embj.201284290 |
Ejemplares similares
-
In Vivo RNAi Rescue in Drosophila melanogaster with Genomic Transgenes from Drosophila pseudoobscura
por: Langer, Christoph C. H., et al.
Publicado: (2010) -
Three-Dimensional Reconstruction and Segmentation of Intact Drosophila by Ultramicroscopy
por: Jährling, Nina, et al.
Publicado: (2010) -
Absence of Ret Signaling in Mice Causes Progressive and Late Degeneration of the Nigrostriatal System
por: Kramer, Edgar R, et al.
Publicado: (2007) -
Aconitase Causes Iron Toxicity in Drosophila pink1 Mutants
por: Esposito, Giovanni, et al.
Publicado: (2013) -
The Complex I Subunit NDUFA10 Selectively Rescues Drosophila pink1 Mutants through a Mechanism Independent of Mitophagy
por: Pogson, Joe H., et al.
Publicado: (2014)