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DNA bending facilitates the error-free DNA damage tolerance pathway and upholds genome integrity

DNA replication is sensitive to damage in the template. To bypass lesions and complete replication, cells activate recombination-mediated (error-free) and translesion synthesis-mediated (error-prone) DNA damage tolerance pathways. Crucial for error-free DNA damage tolerance is template switching, wh...

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Detalles Bibliográficos
Autores principales: Gonzalez-Huici, Victor, Szakal, Barnabas, Urulangodi, Madhusoodanan, Psakhye, Ivan, Castellucci, Federica, Menolfi, Demis, Rajakumara, Eerappa, Fumasoni, Marco, Bermejo, Rodrigo, Jentsch, Stefan, Branzei, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983681/
https://www.ncbi.nlm.nih.gov/pubmed/24473148
http://dx.doi.org/10.1002/embj.201387425