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Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2
Hypoxia is central to both ischaemic and neoplastic diseases. However, the non-coding transcriptional response to hypoxia is largely uncharacterized. We undertook integrated genomic analyses of both non-coding and coding transcripts using massively parallel sequencing and interfaced this data with p...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983684/ https://www.ncbi.nlm.nih.gov/pubmed/24363272 http://dx.doi.org/10.1002/embr.201337642 |