FGF23 promotes renal calcium reabsorption through the TRPV5 channel

αKlotho is thought to activate the epithelial calcium channel Transient Receptor Potential Vanilloid-5 (TRPV5) in distal renal tubules through its putative glucuronidase/sialidase activity, thereby preventing renal calcium loss. However, αKlotho also functions as the obligatory co-receptor for fibro...

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Detalles Bibliográficos
Autores principales: Andrukhova, Olena, Smorodchenko, Alina, Egerbacher, Monika, Streicher, Carmen, Zeitz, Ute, Goetz, Regina, Shalhoub, Victoria, Mohammadi, Moosa, Pohl, Elena E, Lanske, Beate, Erben, Reinhold G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983685/
https://www.ncbi.nlm.nih.gov/pubmed/24434184
http://dx.doi.org/10.1002/embj.201284188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983685/
https://www.ncbi.nlm.nih.gov/pubmed/24434184
http://dx.doi.org/10.1002/embj.201284188

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