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The long non-coding RNA Paupar regulates the expression of both local and distal genes

Although some long noncoding RNAs (lncRNAs) have been shown to regulate gene expression in cis, it remains unclear whether lncRNAs can directly regulate transcription in trans by interacting with chromatin genome-wide independently of their sites of synthesis. Here, we describe the genomically local...

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Detalles Bibliográficos
Autores principales: Vance, Keith W, Sansom, Stephen N, Lee, Sheena, Chalei, Vladislava, Kong, Lesheng, Cooper, Sarah E, Oliver, Peter L, Ponting, Chris P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983687/
https://www.ncbi.nlm.nih.gov/pubmed/24488179
http://dx.doi.org/10.1002/embj.201386225