Automation and validation of micronucleus detection in the 3D EpiDerm™ human reconstructed skin assay and correlation with 2D dose responses

Recent restrictions on the testing of cosmetic ingredients in animals have resulted in the need to test the genotoxic potential of chemicals exclusively in vitro prior to licensing. However, as current in vitro tests produce some misleading positive results, sole reliance on such tests could prevent...

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Detalles Bibliográficos
Autores principales: Chapman, K. E., Thomas, A. D., Wills, J. W., Pfuhler, S., Doak, S. H., Jenkins, G. J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Original Manuscript
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983754/
https://www.ncbi.nlm.nih.gov/pubmed/24675152
http://dx.doi.org/10.1093/mutage/geu011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983754/
https://www.ncbi.nlm.nih.gov/pubmed/24675152
http://dx.doi.org/10.1093/mutage/geu011

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