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Novel antibody binding determinants on the capsid surface of serotype O foot-and-mouth disease virus

Five neutralizing antigenic sites have been described for serotype O foot-and-mouth disease viruses (FMDV) based on monoclonal antibody (mAb) escape mutant studies. However, a mutant virus selected to escape neutralization of mAb binding at all five sites was previously shown to confer complete cros...

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Detalles Bibliográficos
Autores principales: Asfor, Amin S., Upadhyaya, Sasmita, Knowles, Nick J., King, Donald P., Paton, David J., Mahapatra, Mana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983758/
https://www.ncbi.nlm.nih.gov/pubmed/24584474
http://dx.doi.org/10.1099/vir.0.060939-0